![]() ![]() This work was conducted in conjunction with a repetitive compression wave injury paradigm in rats in order to better understand how the wave generation correlates with histopathologic deficits.įinite volume modelling apoptosis compression wave pre-clinical model traumatic brain injury. In this interdisciplinary work, numerical simulations were performed to study the creation of compression waves in an experimental model. While the concept of linking duration and intensity of impact to subsequent histopathologic deficits makes sense, numerical modelling of compression waves has not been performed in this context. Understanding compression wave properties and mechanical loading could help link the histopathologic deficits seen in rodents to what might be happening in human brains following concussions. Humans, however, infrequently succumb to mild traumatic brain injuries and, therefore, the intensity and magnitude of impacts must be inferred. Mild traumatic brain injuries activate similar neuroinflammatory cascades, cell death markers and increases in amyloid precursor protein in both humans and rodents. In a transverse wave, the disturbance that makes up the wave is perpendicular to. The clinical relevance of compression wave injury models revolves around the ability to produce consistent histopathologic deficits. Longitudinal waves are also referred to as compression waves. These vibrations transfer to the string, which functions as a conduit all the way to the other can. In order to improve understanding of acute injury mechanisms, appropriately designed pre-clinical models must be utilized. SWE has a promising role in determining the severity of disease and treatment follow-up of various musculoskeletal tissues including tendons, muscles, nerves, and ligaments. Lesson - Labeling Compression Waves Educational Resources K12 Learning. A compression wave does the same thing: it is a wave where we have some areas with particles that are densely piled close together. The compression wave propagates ahead of the train at local speed of sound. In total, 3.8 million concussions occur each year in the US leading to acute functional deficits, but the underlying histopathologic changes that occur are relatively unknown. Shear waves propagate faster through stiffer contracted tissue, as well as along the long axis of tendon and muscle. Has your knowledge of sound waves reached its crest Probably not, so you can get. A compression wave is generated due to a piston effect as a high-speed train enters a railway tunnel. ![]()
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